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EM: Nano and micro plastic effects on human health (EM-1067)
Collapse All
Expand AllEM Identity and Description
EM Identification
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EM ID
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EM-1067 |
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EM Short Name
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Plastic effects on human health |
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EM Full Name
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Nano and micro plastic effects on human health |
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EM Source or Collection
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None |
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EM Source Document ID
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505 |
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Document Author
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Winearska, E., Jutel, M., and M. Zemelka-Wiacek |
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Document Year
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2024 |
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Document Title
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The potential impact of nano- and microplastics on human health: Understanding human health risks |
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Document Status
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Peer reviewed and published |
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Comments on Status
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Published journal manuscript |
Software and Access
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Contact Name
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Magdalena Zemelka-Wiacek |
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Contact Address
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Department of Clinical Immunology, Wroclaw Medical University, Parkowa 34, Wroclaw, 51-616, Poland |
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Contact Email
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magdalena.zemelka-wiacek@umw.edu.pl |
EM Description
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Summary Description
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ABSTRACT: "Plastics are used all over the world. Unfortunately, due to limited biodegradation, plastics cause a significant level of environmental pollution. The smallest recognized to date are termed nanoplastics (1 nm [nm] up to 1 μm [μm]) and microplastics (1 μm–5 mm). These nano- and microplastics can enter the human body through the respiratory system via inhalation, the digestive tract via consumption of contaminated food and water, or penetration through the skin via cosmetics and clothes contact. Bioaccumulation of plastics in the human body can potentially lead to a range of health issues, including respiratory disorders like lung cancer, asthma and hypersensitivity pneumonitis, neurological symptoms such as fatigue and dizziness, inflammatory bowel disease and even disturbances in gut microbiota. Most studies to date have confirmed that nano- and microplastics can induce apoptosis in cells and have genotoxic and cytotoxic effects. Understanding the cellular and molecular mechanisms of plastics’ actions may help extrapolate the risks to humans. The article provides a comprehensive review of articles in databases regarding the impact of nano- and microplastics on human health. The review included retrospective studies and case reports of people exposed to nanoplastics and microplastics. This research highlights the need for further research to fully understand the extent of the impact of plastics on human health. " |
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Specific Policy or Decision Context Cited
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N/A |
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Biophysical Context
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Not reported |
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EM Scenario Drivers
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N/A |
EM Relationship to Other EMs or Applications
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Method Only, Application of Method or Model Run
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Method Only |
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New or Pre-existing EM?
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New or revised model |
Related EMs (for example, other versions or derivations of this EM) described in ESML
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Document ID for related EM
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None |
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EM ID for related EM
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None |
EM Modeling Approach
EM Relationship to Time
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EM Temporal Extent
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Not applicable |
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EM Time Dependence
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Not applicable |
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EM Time Reference (Future/Past)
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Not applicable |
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EM Time Continuity
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Not applicable |
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EM Temporal Grain Size Value
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Not applicable |
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EM Temporal Grain Size Unit
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Not applicable |
EM Spatial Extent
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Bounding Type
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Not applicable |
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Spatial Extent Name
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Not applicable |
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Spatial Extent Area (Magnitude)
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Not applicable |
Spatial Distribution of Computations
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EM Spatial Distribution
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spatially lumped (in all cases) |
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Spatial Grain Type
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Not applicable |
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Spatial Grain Size
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Not applicable |
EM Structure and Computation Approach
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EM Computational Approach
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Analytic |
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EM Determinism
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deterministic |
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Statistical Estimation of EM
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Model Checking Procedures Used
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Model Calibration Reported?
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Not applicable |
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Model Goodness of Fit Reported?
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Not applicable |
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Goodness of Fit (metric| value | unit)
em.detail.goodnessFitValuesHelp
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None |
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Model Operational Validation Reported?
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Not applicable |
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Model Uncertainty Analysis Reported?
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Not applicable |
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Model Sensitivity Analysis Reported?
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Not applicable |
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Model Sensitivity Analysis Include Interactions?
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Not applicable |
EM Locations, Environments, Ecology
Location of EM Application
Terrestrial location (Classification hierarchy: Continent > Country > U.S. State [United States only])
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| None |
Marine location (Classification hierarchy: Realm > Region > Province > Ecoregion)
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| None |
Centroid Lat/Long (Decimal Degree)
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Centroid Latitude
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Not applicable |
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Centroid Longitude
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Not applicable |
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Centroid Datum
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Not applicable |
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Centroid Coordinates Status
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Not applicable |
Environments and Scales Modeled
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EM Environmental Sub-Class
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Not applicable |
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Specific Environment Type
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Not applicable |
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EM Ecological Scale
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Not applicable |
Scale and taxa of organisms modeled
Scale of differentiation of organisms modeled
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EM Organismal Scale
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Not applicable |
Taxonomic level and name of organisms or groups identified
taxonomyHelp
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| None Available |
EnviroAtlas URL
em.detail.enviroAtlasURLHelp
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| None Available |
EM Ecosystem Goods and Services (EGS) potentially modeled, by classification system
CICES v 4.3 - Common International Classification of Ecosystem Services (Section > Division > Group > Class)
em.detail.cicesHelp
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| None |
(Environmental Subclass > Ecological End-Product (EEP) > EEP Subclass > EEP Modifier)
fegs2Help
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| None |
EM Variable Names (and Units)
Predictor
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Driving Variables (and Units)
view details (5 variables)
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Constant or Factor Variables (and Units)
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None |
Intermediate
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Intermediate (Computed) Variables (and Units)
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None |
Response
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Observed Response Variables (and Units)
view details (7 variables)
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Computed Response Variables (and Units)
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None |